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Influenza continues to be a significant health care issue. Although vaccination is the major line of defense, antiviral drugs play an important role in prophylaxis and disease management. Approved drugs for influenza are currently limited to those that target the viral matrix protein or neuraminidase enzyme. Resistance-associated sequence changes in the genes encoding these proteins have been ...

PDF | On Oct 15, 2010, Ha T Nguyen and others published Recovery of a Multidrug-Resistant Strain of Pandemic Influenza A 2009 (H1N1) Virus Carrying a …

The Effect of Grain Boundary State on Deformation. K R Czerwinski : 5 K Siegien-Iwaniuk : 5 K Steffensen : 5, V I Mishin : 5 W Kutschera : 5 W Nazarewicz : 5 W R Plass : 5 Y A Bliodze : 5Zener Pinning of Grain Boundaries and Structural Stability of Immiscible Alloys RK KOJU,1 KA DARLING,2 LJ KECSKES,2 and Y,"The Effect of Grain Boundary State on Deformation Process Development in ...

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Study of Oseltamivir and Zanamivir Resistance-Related Mutations in Influenza Viruses Isolated from Wild Mallards in Sweden

r224k crashar mishin p. Tolerance to carbon tetrachloride in carbon tetrachloride-. Ilya Tsyrlov, Vladimir Mishin, Vyacheslav Lyakhovich, Resistance of . Get PDF (724K) More content like this Find more content: like this. Read More. Microplate versus continuum descriptions of active tectonic .

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Mishin VP, Hayden FG, Gubareva LV. Susceptibilities of antiviral‐resistant influenza viruses to novel neuraminidase inhibitors. Antimicrob Agents Chemother. 2005; 49 (11):4515‐4520. [PMC free article] [Google Scholar]

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Furthermore, only R224K confers an inhibition of more than 100 fold. Of note, mutation S227N occurs not only in H5N1, but in H1N1 (including H1N1pdm09) albeit with slightly reduced inhibition (4–8 fold). ... Mishin V P, Deyde V M, Sleeman K, Nguyen H T, Sheu T G, Garten R J and Shaw M W 2010 Antiviral Therapy 15 1151. Crossref Google Scholar ...

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Nguyen H T Sheu T G Mishin V P Klimov A I Gubareva L V 2010 Antimicrob. Agents Chemother. 54 3671 [43] Sleeman K Mishin V P Guo Z Garten R J Balish A Fry A M Villanueva J Stevens J Gubareva L V 2014 Antimicrob. Agents Chemother. 58 2045 [44] Nguyen H T Trujillo A A Sheu T G Levine M Mishin V P Shaw M Ades E W Klimov A I Fry A M Gubareva L V ...

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Contribute to mishin/p5-mop development by creating an account on GitHub.... testing 1, 2, 3. Contribute to mishin/p5-mop development by creating an account on GitHub. ...

The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Viruses Surveillance System (KINRESS) to monitor epidemics of influenza and Severe Acute Respiratory Infection (SARI) to identify mutated influenza viruses affecting drug resistance ...